Influence of Kupffer cells on hepatic signal transduction as demonstrated by second messengers and n

• 作 者: HongDing Jie-AnHuang JingTong
• 机 构: DepartmentofPharmacology,DepartmentofInternalMedicine,DepartmentofInternalMedicine
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年11期
• 关键词: 肝信号转导 核转录因子 枯否氏细胞 发射电子显微镜 动物实验 肝脏损伤
• 基金项目: 湖北省武汉市青年科技'晨光计划'项目，湖北省自然科学基金

AIM: To understand the influence of Kupffer cell (KC) on signal transduction pathways in the liver.METHODS: To decrease selectively the number and function of KC, Kunming mice were ip injected with a single dose of gadolinium chloride (GdCl3, 20 mg.kg-1),