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目的:探讨早发型重度子痫前期患者的临床特点和对妊娠结局的影响。方法:对天津医科大学总医院产科2007年1月～2009年12月收治的78例早发型重度子痫前期病例进行分析,根据其发病孕周分为3组,即A组(孕周<28周),B组(28周≤孕周<32周),C组(32周≤孕周<34周)。结果:早发型重度子痫前期3组患者并发症发生率无统计学意义(P>0.05);3组间新生儿窒息率和围产儿死亡率均有统计学意义(P<0.05);B组期待治疗时间明显长于其他两组(P<0.05)。结论:早发型重度子痫前期新生儿窒息和围产儿死亡率随发病孕周延长而降低,应严格选择病例进行期待治疗,并严密监测母胎情况,适时选择合适的终止妊娠方式。
Objective: To investigate the clinical features of early-onset severe preeclampsia and its effect on pregnancy outcome. Methods: Seventy eight cases of early-onset severe preeclampsia were collected from January 2007 to December 2009 in the General Hospital of Tianjin Medical University. Patients were divided into three groups according to their gestational age (group A, gestational age <28 Week), group B (28 weeks ≤ gestational weeks <32 weeks), group C (32 weeks ≤ gestational weeks <34 weeks). Results: There was no significant difference in the incidence of complications among the three groups (P> 0.05). The rates of neonatal asphyxia and perinatal mortality were significantly different between the three groups (P <0.05) Expect the treatment time was significantly longer than the other two groups (P <0.05). Conclusions: Asphyxia and perinatal mortality in premature new onset severe preeclampsia decrease with the prolongation of gestational weeks. Patients should be selected carefully for expectant treatment. The condition of the mother fetus should be closely monitored and appropriate termination of pregnancy should be chosen timely.