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采用 QDR2 0 0 0型双能 X线骨密度测定仪观察中药密骨片与西药利维爱对绝经后妇女骨密度及骨代谢的影响。结果显示 ,经密骨片与利维爱治疗 6个月后 ,两组腰椎、股骨颈、粗隆处骨密度及 E2 测定值略有上升 ,与治疗前比较经 t检验无明显差异 (P>0 .0 5 ) ;密骨片组治疗 6个月后股骨三角区骨密度及血清碱性磷酸酶明显上升 ;尿钙与肌酐比值、尿羟脯氨酸与肌酐比值明显下降 ,与治疗前比较有显著差异 (P<0 .0 5 )。提示密骨片具有抑制骨丢失和促进骨形成作用。
The QDR200 0 dual-energy X-ray absorptiometry was used to observe the effects of Chinese medicine Migu tablets and Xiwei Liweiai on bone mineral density and bone metabolism in postmenopausal women. The results showed that BMD and E2 measured at the lumbar spine, femoral neck, and trochanter increased slightly after treatment with Tiegu tablets and Liwei Ai for 6 months. There was no significant difference between the two groups before and after treatment. 0. 0 5 ) ; Bone mineral density and serum alkaline phosphatase in the femoral triangle were significantly increased after 6 months of treatment in the Miju Tablet group; the ratio of urinary calcium to creatinine and the ratio of hydroxyproline to creatinine were significantly decreased compared with before treatment. There was a significant difference (P<0.05). It is suggested that TMD can inhibit bone loss and promote bone formation.