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对30例十二指肠溃疡(Du)患者和15例正常对照者进行了消化间期移行性复合运动波(MMC)的检测及血浆胃动素(MTL)、生长抑素(SS)的放免测定.结果显示:Du患者MMC正常者仅为16.7%,明显低于对照组(60%,P<0.001)且胃窦MMCⅢ期持续时间缩短(P<0.05);胃窦、十二指肠近端MMCⅡ期的收缩频率、收缩波幅均较对照组减少(P<0.05,P<0.001)。Du患者MMCⅡ、Ⅲ期的MTL明显低于对照组(P<0.05),而SS则高于对照组(P<0.05,P<0.55).结果提示:胃肠道运动异常和胃肠激素的释放与Du有着密切关系。
Thirty patients with duodenal ulcer (Du) and 15 normal controls were enrolled in the study. The interphase motility complex motor wave (MMC) and the levels of plasma motilin (MTL), somatostatin (SS) Determination. The results showed that: Du patients with normal MMC was only 16.7%, significantly lower than the control group (60%, P <0.001), and gastric antrum MMC duration decreased (P <0.05); gastric antrum, The frequency of contractions and the amplitude of contractions in the proximal MMC Ⅱ phase were lower than those in the control group (P <0.05, P <0.001). Du patients with MMC Ⅱ, Ⅲ MTL was significantly lower than the control group (P <0.05), while the SS was higher than the control group (P <0.05, P <0.55). The results suggest that: abnormal gastrointestinal motility and gastrointestinal hormone release and Du are closely related.