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为探讨妇科病人应用止血药与下肢深静脉血栓形成发病的关系,回顾性分析1992～1996年间125例50岁以上妇科手术病人术后下肢深静脉血栓形成的发生情况。术前及术后应用止血药者为Ⅰ组(74例);有轻度心血管疾病并同时应用扩血管药及止血药者为Ⅱ组(17例);合并高血压和(或)糖尿病应用扩血管或抗凝药而未用止血药者为Ⅲ组(14例);不合并心血管疾病且未用抗凝及止血药者为Ⅳ组(20例)。结果表明,Ⅰ组下肢深静脉血栓形成发生率为10.8%,明显高于Ⅲ组(0%)及Ⅳ组(5%)(P<0.01)。结论:止血药可增加妇科手术后下肢深静脉血栓形成发生率,不宜常规应用。
To investigate the relationship between hemostatic agents and the incidence of deep venous thrombosis in lower extremities in gynecologic patients, the incidence of postoperative deep venous thrombosis in 125 patients with gynecological surgery over the age of 50 from 1992 to 1996 was retrospectively analyzed. Preoperative and postoperative hemostatic agents were group Ⅰ (74 cases); patients with mild cardiovascular disease and vasodilators and hemostatic agents were group Ⅱ (n = 17); patients with hypertension and / or diabetes Vasodilators or anticoagulants without hemostatic were Group Ⅲ (14 cases); without cardiovascular disease and no anticoagulant and hemostatic drugs were Group Ⅳ (20 cases). The results showed that the incidence of deep vein thrombosis in group Ⅰ was 10.8%, which was significantly higher than that in group Ⅲ (0%) and Ⅳ (5%) (P <0.01). Conclusion: Hemostatic drugs can increase the incidence of lower extremity deep vein thrombosis after gynecological surgery, should not be routinely used.