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目的了解2009年深圳南山区流行性感冒的病原学流行情况,探讨流感流行规律,做好流感预防控制工作。方法常年采集流感样病例标本,病毒分离鉴定方法按《流行性感冒病毒及其实验技术》[1]进行。结果全年检测标本538份,分离出流感病毒173株,分离率32.2%。其中13株为H1N1亚型,占7.5%;58株为H3N2亚型,占33.5%;27株为BV亚型,占15.6%;3株为BY亚型,占1.7%;72株新甲型H1N1,占42.4%。1~5月份以BV、H1N1、H3N2亚型流感病毒流行为主,6月份开始以H3N2流感病毒流行为主,进入8月份新甲型H1N1流感病毒出现,并于9~12月成为流行的优势株。0~、5~及其余3组合并的阳性率比较,差异有统计学意义(χ2=18.443,P<0.05),结论2009年南山区流感流行出现2个高峰期,但是与往年不同的是第2高峰期从7月一直持续到12月份,7~8月份以季节性流感流行为主,9~12月以新甲型H1N1为主,而新甲型H1N1亚型暴发流行成为当年的高检出率的优势流行株。
Objective To understand the epidemic situation of influenza in Nanshan District of Shenzhen in 2009, discuss the epidemic rule of influenza and do a good job in influenza prevention and control. Methods The samples of influenza-like cases were collected year-round, and the method of virus isolation and identification was carried out according to “Influenza virus and its experimental technique” [1]. Results A total of 538 samples were tested in the whole year, and 173 strains of influenza viruses were isolated with a separation rate of 32.2%. Among them, 13 were H1N1 subtypes, accounting for 7.5%, 58 were H3N2 subtypes (33.5%), 27 were BV subtypes (15.6%), 3 were BY subtypes (1.7%), 72 H1N1, accounting for 42.4%. From January to May, the epidemic of BV, H1N1 and H3N2 subtypes was the major influenza virus. Influenced by the prevalence of H3N2 influenza virus in June, new influenza A (H1N1) virus emerged in August and became prevalent in September and December Strain. The difference was statistically significant (χ2 = 18.443, P <0.05). Conclusions There were two peak periods of influenza epidemic in Nanshan District in 2009, but the differences with the previous years were 2 peak from July until December, July to August mainly seasonal influenza epidemic, 9 to 12 months to the new H1N1-based, and the new H1N1 subtype outbreak became the high-seizure The prevalence rate of popular strains.