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目的:探讨超敏C-反应蛋白(hs-CRP)与碱性磷酸酶积分(NAP)的检测在感染病例中的数值变化及相关性,评价其诊断价值。方法:收集已明确诊断为细菌感染患者60例,非感染疾病患者30例,对其hs-CRP及NAP积分进行检测,并对其差异及相关性进行比较分析。结果:与非感染组相比,细菌感染患者的hs-CRP值、NAP积分均显著升高(P<0.01),两者阳性率比较差异无统计学意义(P>0.05),但具有相关性(r=0.861,P<0.01)。以8 mg/L为界限,hs-CRP的灵敏度为81.7%,特异性为73.3%;以100为界限,NAP积分的灵敏度为73.3%,特异性为76.7%。结论:hs-CRP和NAP积分均可作为细菌感染的辅助检查,但hs-CRP灵敏度更高,NAP积分特异性更高,可结合使用。
OBJECTIVE: To investigate the changes and correlations between hs-CRP and alkaline phosphatase (NAP) in the infected cases and evaluate their diagnostic value. Methods: Sixty patients with confirmed bacterial infection and 30 patients with non-infectious diseases were collected and their hs-CRP and NAP scores were tested. The differences and correlations were also analyzed. Results: The hs-CRP and NAP scores of patients with bacterial infection were significantly higher than those of non-infected patients (P <0.01), but there was no significant difference between the two groups (P> 0.05) (r = 0.861, P <0.01). With 8 mg / L as the limit, hs-CRP had a sensitivity of 81.7% and a specificity of 73.3%. For a cutoff of 100, the NAP score had a sensitivity of 73.3% and a specificity of 76.7%. CONCLUSIONS: Both hs-CRP and NAP scores can be used as auxiliary tests for bacterial infection. However, hs-CRP is more sensitive and has a higher NAP integral specificity and can be used in combination.