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血管紧张素Ⅱ在糖尿病肾病发病中的作用胡伟新龚德华综述关键词血管紧张素Ⅱ糖尿病肾病发病机制肾小球、肾小管肥大,基底膜增厚,肾小球高灌注、高压力及微量白蛋白尿是糖尿病肾病(DN)的早期特征。大量细胞外基质成分在小球系膜区进行性沉积,则导致小球血管袢减少,...
Role of angiotensin Ⅱ in the pathogenesis of diabetic nephropathy HU Wei-xin, GONG De-hua Key words Angiotensin Ⅱ Pathogenesis of diabetic nephropathy Glomeruli, tubular hypertrophy, thickening of basement membrane, high glomerular perfusion, high pressure and microalbuminuria Is an early feature of diabetic nephropathy (DN). A large number of extracellular matrix components in the small area of the mesangial deposition, then lead to reduced glomerular 袢, ...