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目的:评价榄香烯乳加联合化疗治疗难治性急性非淋巴细胞白血病。方法:将30 例白血病患者随机分为治疗组:用榄香烯乳300mg 入5 % G.S500ml 中静脉滴注,持续用药14 天,同时用联合化疗:Ara- C0.5g/m2.d ,第1~7 天;VP- 16 100mg/m2.d ,第1 ~3 天;对照组单用联合化疗,方案用量用法同治疗组。结果:治疗组总有效率77.8 % ,对照组总有效率50 % ,差异有显著性( P< 0.05)。结论:榄香烯乳对难治性急性非淋巴细胞白血病(ANLL)有肯定疗效,比单用联合化疗效果好,且不良反应少,无血象和骨髓抑制。
Objective: To evaluate the treatment of refractory acute non-lymphocytic leukemia with elemene plus chemotherapy. METHODS: Thirty patients with leukemia were randomly divided into treatment groups: 300 mg of elemene milk into 5% G. Intravenous infusion of S500ml for 14 days, combined with chemotherapy: Ara-C0.5g/m2. d, 1 to 7 days; VP-16 16 mg/m2. d, the first 1 to 3 days; control group alone with chemotherapy, regimen usage and treatment group. Results: The total effective rate was 77.8 % in the treatment group and 50% in the control group, with a significant difference (P < 0.05). Conclusion: Elemene milk has a positive effect on refractory acute non-lymphocytic leukemia (ANLL). It is more effective than single combination chemotherapy and has fewer adverse reactions. There is no blood and bone marrow suppression.