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目的探讨牙周病与妊娠不良事件的关系。方法前瞻性比较2008年6月-2009年12月间中山三院产检并分娩的66例确诊牙周病的孕妇(观察组)及同期80例口腔健康的孕妇(对照组)的临床资料,比较两组妊娠并发症、合并症及围产儿结局等的差异。结果观察组细菌性阴道炎、早产、胎儿发育迟缓、胎膜早破和新生儿低体质量(SGA)的发生率分别为63.60%(42/66)、12.12%(8/66)、13.60%(9/66)、34.80%(23/66)和7.58%(5/66),对照组为31.25%(25/80)、3.75%(3/80)、2.27%(2/80)、16.25%(13/80)和2.50%(2/80),两组间比较差异有统计学意义(P<0.01)。结论牙周病孕妇的并发症(细菌性阴道炎、早产、胎儿发育迟缓、胎膜早破)和新生儿低体质量(SGA)发生率明显高于口腔健康的妇女,临床上应给予重视,加强孕前及妊娠期间的口腔保健,提高围产质量。
Objective To investigate the relationship between periodontal disease and adverse events of pregnancy. Methods The clinical data of 66 pregnant women diagnosed as periodontal disease (observation group) and 80 healthy oral pregnant women (control group) from June 2008 to December 2009 were prospectively compared. Two groups of pregnancy complications, complications and perinatal outcomes and other differences. Results The incidences of bacterial vaginosis, preterm labor, fetal retardation, premature rupture of membranes and low birth weight (SGA) in observation group were 63.60% (42/66), 12.12% (8/66) and 13.60% (25/80), 3.75% (3/80), 2.27% (2/80), 16.25 (25/80) in the control group, % (13/80) and 2.50% (2/80), respectively. The difference between the two groups was statistically significant (P <0.01). Conclusion The incidence of complications of periodontal disease pregnant women (bacterial vaginosis, premature birth, fetal retardation, premature rupture of membranes) and neonates with low body mass (SGA) was significantly higher than that of oral health, clinically should pay attention, Strengthen oral health care during pregnancy and pregnancy to improve perinaton quality.