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目的:探讨甲亢性肝病患者血清检验指标的变化情况及其在疾病判断中的应用价值。方法:回顾性分析2011年7月-2015年8月本院收治的128例甲亢性肝病患者的一般资料,将其按照肝功能情况分为研究组(肝功能异常组,n=64)与对照组(肝功能正常组,n=64)。检测两组患者各项生化指标,并对组间差异进行对比。结果:研究组患者丙氨酸转氨酶、谷氨酰转肽酶、碱性磷酸酶、天冬氨酸转氨酶、血清总甲状腺素、血清促甲状腺素水平均高于对照组,结果有显著性差异(P<0.05);研究组、对照组患者总胆汁酸水平对比,结果无显著性差异(P>0.05)。结论:肝功能异常是甲亢性肝病患者常见的临床表现,临床上需加强对患者血清检验指标的检查,一旦其出现异常,应考虑肝功能损伤,需及时进行积极治疗。
Objective: To investigate the change of serum test index and its application value in the judgment of disease in patients with hyperthyroidism liver disease. Methods: A retrospective analysis was made on the general data of 128 patients with hyperthyroidism with liver disease admitted from July 2011 to August 2015 in our hospital. The patients were divided into study group (liver dysfunction group, n = 64) and control group Group (normal liver function group, n = 64). The biochemical indexes of two groups were detected, and the differences between groups were compared. Results: The levels of alanine aminotransferase, glutamyl transpeptidase, alkaline phosphatase, aspartate aminotransferase, serum total thyroxine and serum thyrotropin in the study group were significantly higher than those in the control group P <0.05). There was no significant difference in total bile acid levels between study group and control group (P> 0.05). Conclusion: Abnormal liver function is a common clinical manifestation in patients with Hyperthyroidism Liver Disease. Clinically, it is necessary to strengthen the examination of serum test indicators in patients. Once abnormal, liver function impairment should be considered and active treatment should be timely.