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目的分析与研究乳腺癌新辅助化疗中超声引导下粗针穿刺活检的临床疗效。方法本文选择了80例乳腺癌患者进行调查研究。对该80例患者采用超声引导下粗针穿刺活检的辅助化疗方法,并进行根治性手术。对术前穿刺活检与术后所提取的标本进行病理检查,观察分析患者腋窝淋巴结、原癌基因蛋白(C-erbB-2)、乳腺原发灶以及存在于癌组织中的雌孕激素受体(ER、PR)、乳腺纤维瘤、乳腺增生等的变化与表达。结果患者在超声引导下粗针穿刺活检的标本与术后标本病理结果相比较,符合率为98.1%,且经新辅助化疗后腋窝淋巴结、乳腺原发灶均出现明显改善。结论新辅助化疗中超声引导下粗针穿刺活检有助于判断乳腺癌对所用药物及治疗方法的敏感度,在术前了解患者病情,可提高药物的针对性及治疗方法的有效性,减轻患者病痛,安全、可靠,值得在临床上实施与推广。
Objective To analyze and study the clinical efficacy of ultrasound-guided needle biopsy in neoadjuvant chemotherapy of breast cancer. Methods 80 cases of breast cancer were selected for investigation. The 80 patients underwent ultrasound guided needle biopsy of the adjuvant chemotherapy, and radical surgery. Preoperative biopsy and postoperative specimens were collected for histopathological examination. The axillary lymph node, proto-oncogene protein (C-erbB-2), primary breast tumor and estrogen and progesterone receptor (ER, PR), breast fibroids, breast hyperplasia and other changes and expression. Results Comparing the pathological results of the needle-guided biopsy with the needle-guided biopsy, the coincidence rate was 98.1%. The axillary lymph nodes and primary breast lesions were significantly improved after neoadjuvant chemotherapy. Conclusions Ultrasound-guided needle biopsy in neoadjuvant chemotherapy can help to determine the sensitivity of breast cancer to the drugs used and the method of treatment. To understand the patient’s condition before surgery can improve the pertinence of the drug and the effectiveness of the treatment, Suffering, safe, reliable, it is worth clinical implementation and promotion.