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目的:探讨临床药师干预对于提高围术期预防性应用抗菌药物的合理性作用效果。方法:选取浙江省丽水市松阳县人民医院实施干预前(2012年2~6月)的外科手术患者100例为非干预组,选取该院实施干预后(2013年2~6月)100例手术患者为干预组,对比分析两组围术期抗菌药使用情况。结果:实施临床药师干预后,干预组围术期预防应用抗生素在品种选择、给药时机、用法用量等方面的合理性及抗菌药物费用方面均显著优于非干预组(P<0.05)。结论:临床药师干预可有效提高围术期预防性应用抗菌药物的合理性。
Objective: To investigate the clinical pharmacist intervention for improving perioperative prophylactic use of antimicrobial agents rational effect. Methods: 100 patients who underwent surgical intervention in Songyang County People's Hospital of Lishui City, Zhejiang Province before the intervention (from February to June, 2012) were selected as non-intervention group. 100 cases of surgical operation (from February to June 2013) Patients were intervention group, comparative analysis of two groups of perioperative antibacterial use. Results: After the implementation of clinical pharmacist intervention, the prevention and treatment of perioperative antibiotics in the intervention group was significantly better than the non-intervention group in terms of variety selection, administration timing, dosage and other aspects of rational use and antibacterial drug costs (P <0.05). Conclusion: The intervention of clinical pharmacists can effectively improve the perioperative prophylactic use of antimicrobial agents rationality.