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原发性血小板增多症是骨髓增殖性疾病,伴有骨髓内血小板增多及巨核细胞增生;已证实有血小板功能异常。主要的临床特点是反复发作的自发性出血和/或动脉和静脉系统的血栓形成。中枢神经系统并发症包括有:颈动脉和椎基动脉供血区短暂性脑缺血发作或卒中、颅内出血、头痛;而癫痫或眩晕少见。病程中仅出现神经学症状者罕见。作者报道一例临床仅表现为大脑中动脉供血区脑血管闭塞的原发性血小板增多症。患者,男,30岁。因言语困难、头痛及癫痛发作于1987年12月入院。28岁时病人逐渐感觉说话时
Essential thrombocythemia is a myeloproliferative disease with bone marrow thrombocytosis and megakaryocyte hyperplasia; platelet dysfunction has been demonstrated. The main clinical features are recurrent spontaneous bleeding and / or thrombosis of the arterial and venous systems. Central nervous system complications include: transient ischemic attack or stroke in the carotid and vertebral artery blood supply areas, intracranial hemorrhage, headache; and epilepsy or dizziness rare. Nervous symptoms are rare in the course of the disease. The authors report a case of primary clinical manifestations of cerebral arterial occlusion in the middle cerebral artery occlusion of essential thrombocythemia. Patient, male, 30 years old. Due to speech difficulties, headache and epileptic seizures in December 1987 admitted. 28-year-old patient gradually feel when talking