论文部分内容阅读
目的研究阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者清醒和睡眠时上气道阻塞的情况及其变化。方法21例OSAHS患者经20h无睡眠后,分别在清醒与睡眠状态下,获得上气道正中矢状面的动态MRI影像。配对t检验比较清醒和睡眠时上气道阻塞区长度的差异。结果12例OSAHS患者清醒时有腭咽区阻塞,21例患者睡眠时均有腭咽区阻塞,清醒时和睡眠时腭咽区阻塞的符合百分比为57·14%。12例患者清醒时上气道阻塞区长度的最大值(2·99±0·51)cm、最小值(0·72±0·23)cm,两者差值(2·27±0·67)cm,分别比睡眠时的最大值(6·61±1·23)cm、最小值(0·95±0·22)cm、两者差值(5·66±1·27)cm小,差异均有统计学意义(P<0·01)。结论OSAHS患者睡眠时上气道的阻塞是变化的、多区域的。OSAHS患者清醒时上气道的阻塞仅在一定程度上提示睡眠时的阻塞情况。
Objective To investigate the changes of upper airway obstruction during awake and sleep in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods Twenty-one OSAHS patients underwent no dynamic sleep for 20 hours, and then obtained the dynamic MRI images of the mid-upper sagittal plane under awake and sleep conditions respectively. Paired t-test compared awake and sleep on the length of the upper airway obstruction difference. Results In 12 OSAHS patients, there was obstruction of the velopharyngeal area when awake. In the 21 patients, the obstruction of the velopharyngeal area was obstructed. The coincidence percentage of obstructive velopharyngeal area in awake and sleep was 57.14%. The maximum length of upper airway obstruction in conscious patients was (2.99 ± 0.51) cm, the minimum was (0.72 ± 0.23) cm, the difference between them was (2.27 ± 0.67) ) cm, respectively, than the maximum sleep time (6 · 61 ± 1 · 23) cm, the minimum (0 · 95 ± 0 · 22) cm, the difference between the two was (5 · 66 ± 1 · 27) The differences were statistically significant (P <0.01). Conclusion Obstructive airway obstruction in OSAHS patients is variable and multi-regional. Upper airway obstruction in patients with OSAHS awake only to some extent prompted sleep obstruction.