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目的分析肝癌筛查效果,了解人群肝癌患病影响因素。方法采取整群抽样方法,共筛查20 282名当地居民,年龄在35~64岁之间,开展癌症相关危险因素和健康知识问卷调查,并按高危人群判定标准,筛选出符合筛查条件的高危人群,经知情同意后,进行血清AFP检测和B超检查。结果检出肝癌7例(其中早期肝癌5例),肝硬化29例(占1.43%),AFP≥20μg/L9例(占0.44%),检出其他肝脏异常736例(占36.2%)。肝癌和肝硬化病例中HBs Ag阳性比例较高,分别为71.4%和65.5%。一般筛查对象和高危人群不同种类膳食摄入差异无统计学意义(χ2=0.307,P>0.05),心理因素中环境适应能力和精神创伤在一般筛查对象与高危人群比较,差异有统计学意义(P<0.05)。结论开展肝癌筛查工作,对早期发现肝癌具有重要作用。
Objective To analyze the screening effect of liver cancer and understand the influencing factors of the prevalence of liver cancer in the population. Methods A total of 20 282 local residents were enrolled in this study. A total of 20 282 local residents aged 35-64 were enrolled in this study. The risk factors of cancer and health knowledge questionnaire were investigated. According to the criteria of high risk population, High-risk groups, after informed consent, serum AFP detection and B-ultrasound. Results Liver cancer was detected in 7 cases (5 cases of early liver cancer), cirrhosis in 29 cases (1.43%), AFP≥20 μg / L in 9 cases (0.44%), and other liver abnormalities were detected in 736 cases (36.2%). The positive proportion of HBsAg in liver cancer and cirrhosis cases was 71.4% and 65.5% respectively. There was no significant difference in dietary intake between general screening subjects and high-risk groups (χ2 = 0.307, P> 0.05). The environmental adaptability and trauma of psychological factors were higher in general screening subjects compared with those in high-risk groups, the difference was statistically significant Significance (P <0.05). Conclusion The screening of liver cancer plays an important role in the early detection of liver cancer.