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目的:探讨老年急性白血病的临床特点。方法:对22例老年急性白血病患者的临床资料进行总结。结果:老年急性白血病的临床表现及血液学改变多不典型,易误诊;除失访或化疗前死亡(13例)外,按病情予DA、COA、COP及小剂量阿糖胞苷方案治疗后,完全缓解2例(用DA等方案),部分缓解3例,死亡4例。结论:老年白血病的临床表现及血液学改变不典型,影响早期诊断;其预后较差,可按上述方案 小剂量化疗,以延长生存期。
Objective: To investigate the clinical features of senile acute leukemia. Methods: The clinical data of 22 elderly patients with acute leukemia were summarized. Results: The clinical manifestations and hematological changes in elderly patients with acute leukemia were mostly atypical and easily misdiagnosed. Except for the loss of follow-up or pre-chemotherapy death (13 cases), the patients were treated with DA, COA, COP and low dose of cytarabine , Complete remission in 2 cases (with DA and other programs), partial remission in 3 cases, 4 deaths. CONCLUSION: The clinical manifestations and hematological changes of atypical leukemia are not typical, which affects the early diagnosis. The prognosis is poor. Small doses of chemotherapy can be used according to the above scheme to prolong the survival period.