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目的:探讨弗明汉卒中风险评估(FSRP)与轻度认知功能损害的相关性。方法:通过对我院神经内科纳入的60名受试者进行血管危险因素调查、弗明汉卒中风险评分和神经心理测验。按照FSRP大小,将受试者分为低危组、中危组及高危组,按照神经心理测评结果将受试者分为NC组和MCI组,并进行相关性分析。结果:随着FSRP增加(即低危组、中危组、高危组),受试者的认知功能呈显著的递减趋势。Pearson相关分析的结果显示,FSRP与认知功能具有显著的线性相关性。结论:在正常人群和有轻度认知功能损害人群中,FSRP与认知功能损害均具有显著相关性,因此FSRP可作为轻度认知功能损害的早期指标,为临床评价认知功能提供了新的方法。
Objective: To investigate the correlation between the risk of stroke risk in Framingham (FSRP) and mild cognitive impairment. Methods: Sixty subjects included in our Department of Neurology were investigated for vascular risk factors, stroke risk scores and neuropsychological tests in Framingham. According to the size of FSRP, the subjects were divided into low-risk group, moderate-risk group and high-risk group. According to the results of neuropsychological evaluation, subjects were divided into NC group and MCI group, and correlation analysis was made. Results: With the increase of FSRP (low risk group, moderate risk group, high risk group), the cognitive function of the subjects showed a significant decreasing trend. Pearson correlation analysis showed that there was a significant linear correlation between FSRP and cognitive function. CONCLUSIONS: There is a significant correlation between FSRP and cognitive impairment in both normal and mildly impaired cognitive functions. Therefore, FSRP can be used as an early indicator of mild cognitive impairment and provide a useful tool for clinical evaluation of cognitive function New method