论文部分内容阅读
目的比较长托宁与阿托品在甲拌磷中毒院前急救中的疗效。方法遴选抢救时间1h以内的甲拌磷中毒患者96例随机分为两组,分别接受长托宁(首次剂量1-6mg)或阿托品(首次剂量2-20mg)治疗,同时第一时间给予氯解磷定0.5-2.5g,肌肉注射,转运完成后进入有机磷中毒诊疗常规,分析长托宁与阿托品在院前应用中对患者预后的影响。结果治疗组死亡2例,呼吸衰竭5例,无中间综合征及反跳发生,平均住院6.5±1.0d;对照组死亡4例,呼吸衰竭5例,中间综合征4例,反跳2例,并发多器官功能衰竭2例,阿托品过量8例,阿托品中毒2例,发生心动过速30例,平均住院10.0±5.0d。结论在院前急救中应用长托宁治疗明显优于阿托品。
Objective To compare the efficacy of penehyclidine and atropine in the premedication of phorate poisoning. Methods Ninety-six patients with phorate poisoning within 1h were selected and randomly divided into two groups. Patients were treated with penehyclidine (first dose 1-6mg) or atropine (first dose 2-20mg) respectively, and the first time they were given chlorine solution Phosphorus 0.5-2.5g, intramuscular injection, transfusion into the routine diagnosis and treatment of organophosphate poisoning, analysis of the long-acting and atropine in the pre-hospital application of the prognosis of patients. Results In the treatment group, there were 2 deaths and 5 respiratory failure cases without intermediate syndrome and rebound occurred, with an average hospital stay of 6.5 ± 1.0 days. There were 4 deaths in the control group, 5 respiratory failure cases, 4 intermediate syndromes, 2 rebound cases, Two cases of multiple organ failure, atropine overdose in 8 cases, atropine poisoning in 2 cases, tachycardia occurred in 30 cases, the average hospitalization 10.0 ± 5.0d. Conclusion The application of penehyclidine in pre-hospital emergency treatment was significantly better than atropine.