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87例轻、中度高血压患者分为二组,A组 44例口服尼群地平,B组 43例口服卡托普利,用药三个月,A组总有效率95.45%,显效率77.27%,B组总有效率67.44%,显效率47.84%,两组总有效率及显效率比较均有显著性差异(P<0.01),三个月后A组有10例,B组有28例舒张压仍未降至正常,加服寿比山后血压均降至正常,血糖、电解质、尿素氮等与治疗前比较无明显变化,部分病人胆固醇升高,但组间无明显差异,提示尼群地平的降压效果明显优于卡托普利,寿比山与尼群地平或卡托普利合用均有协同降压作用。
Eighty-seven patients with mild to moderate hypertension were divided into two groups: 44 patients in group A received nitrendipine, and 43 patients in group B received captopril. The total effective rate in group A was 95.45% and the effective rate was 77.27% . The total effective rate in group B was 67.44%, the effective rate was 47.84%. There was significant difference between the two groups in total effective rate and markedly effective rate (P <0.01). After three months, there were 10 cases in group A and 28 cases in group B Blood pressure did not drop to normal, plus service life than mountain blood pressure dropped to normal, blood glucose, electrolytes, urea nitrogen and no significant change compared with before treatment, some patients with elevated cholesterol, but no significant difference between groups, suggesting that nitric The antihypertensive effect of the ground is obviously superior to that of captopril, and synergistic antihypertensive effect of the combination of the supine mountain and nitrendipine or captopril.