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我国乙肝人数众多,特别是多为慢性,感染往往发生于孩童时代,主要来源于乙肝家族。其自然发展(未予治疗)过程大致可划分为免疫耐受期、免疫清除期(免疫活动期)和感染后恢复或恶化期三个阶段。以下一一介绍: 免疫耐受期 孩童时期感染乙肝病毒是乙肝慢性化的主要因素,年龄越小,发生慢性化的比例越高。乙肝病毒e抗原阳性(俗称“大三阳”)的母亲所生育的子女,如果出生后没有注射乙肝疫苗预防,90％以上会发展为慢性乙肝;乙肝父亲所生育的子女,成为慢性乙肝几率也很高。这种通过父母传染给孩子
A large number of hepatitis B in our country, especially mostly chronic, infection often occurs in childhood, mainly from hepatitis B family. Its natural development (untreated) process can be broadly divided into immune tolerance period, immune clearance period (immune activity period) and post-infection recovery or exacerbation of three stages. The following are introduced: Immune tolerance Childhood infection with hepatitis B virus is the main factor for chronic hepatitis B, the younger, the higher the proportion of chronic. Children born to mothers with hepatitis B e antigen positive (commonly known as “Sanyangyang”) develop more than 90% of chronic hepatitis B if they do not receive hepatitis B vaccine after birth; and children born to hepatitis B High. This is transmitted to children through their parents