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过去普遍认为糖尿病的原因是胰腺分泌的胰岛素减少。日本滋贺大学第三内科的小林正博士通过研究,发现有一种新的类型的糖尿病患者,是由于胰腺分泌“异常的人胰岛素”所致。正常的胰岛素分子是由A 链上的21氨基酸和B 链上的30个氨基酸构成。小林在分析糖尿病患者的胰岛素时,发现B 链上第24位或25位氨基酸与正常胰岛素不同。一般糖尿病患者血中胰岛素浓度都低于正常值,而这类糖尿病患者的胰岛素浓度却高达正常人的8倍。
The reason for diabetes in the past is generally believed to be the reduction of insulin secreted by the pancreas. Dr. Shinsakubo Kobayashi, a member of the third internal medicine department at Shiga University in Japan, has found that there is a new type of diabetes caused by the secretion of “abnormal human insulin” by the pancreas. A normal insulin molecule consists of 21 amino acids on the A chain and 30 amino acids on the B chain. Kobayashi in the analysis of insulin in diabetic patients found that B chain on the 24th or 25th amino acid and normal insulin is different. In general, blood levels of insulin in diabetic patients are lower than normal, but insulin levels in such diabetic patients are as high as 8 times normal.