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目的探讨广西巴马长寿地区长寿老人心血管危险因素与心脑血管事件发生的关系。方法对巴马长寿地区≥90岁的长寿老人212例(长寿老人组)系统调查,了解脑卒中和冠心病事件(事件组)患病情况,通过对比事件组和非事件组血压、血糖、血脂、体质量指数等情况,探讨心脑血管事件发生的相关危险因素。结果巴马长寿老人心脑血管事件患病粗率5.6%(脑卒中2.4%,冠心病3.3%);事件组和非事件组对比:事件组收缩压和低密度脂蛋白胆固醇(LDL-C)水平明显高于非事件组(P<0.05)。吸烟、高血压、高LDL-C血症患病粗率事件组明显高于非事件组(P<0.01或<0.05)。多因素Logistic回归分析表明:吸烟、高血压、高LDL-C和高甘油三酯(TG)血症与长寿老人心脑血管事件呈正相关(P<0.05)。结论巴马长寿老人心脑血管事件患病率较低。吸烟、高血压、高LDL-C和高TG血症与心脑血管事件的发生密切相关,早期预防和干预这些危险因素有助于减少心脑血管事件发生。
Objective To investigate the relationship between cardiovascular risk factors and cardiovascular and cerebrovascular events in longevous elderly in Bama region of Guangxi. Methods A total of 212 elderly people with longevity ≥90 years old in Changbai area of Bama were studied systematically to find out the prevalence of stroke and coronary heart disease (event group). By comparing the blood pressure, blood glucose, blood lipid , Body mass index, etc., to explore the risk factors associated with cardiovascular events. Results The prevalence of cardiovascular and cerebrovascular events in longevity elderly patients in Bama was 5.6% (stroke 2.4% and coronary heart disease 3.3%). Compared with non-event group, systolic blood pressure and LDL-C levels Significantly higher than non-event group (P <0.05). Smoking, high blood pressure, high incidence of severe LDL-C sequelae were significantly higher than those in non-incidents (P <0.01 or <0.05). Multivariate Logistic regression analysis showed that smoking, hypertension, high LDL-C and triglyceride (TG) were positively correlated with cardiovascular events in longevity elderly (P <0.05). Conclusions The prevalence of cardiovascular and cerebrovascular events in longevity elderly is lower in Bama. Smoking, high blood pressure, high LDL-C and high TG are closely related to the occurrence of cardiovascular and cerebrovascular events. Early prevention and intervention of these risk factors can help reduce cardiovascular and cerebrovascular events.