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目的:观察静脉使用拉贝洛尔治疗妊娠高血压危象的疗效。方法:妊娠高血压危象55例患者分为两组,A组(30例)使用拉贝洛尔注射液,以(0.5～1)mg/min速度静脉微泵输入,2h左右血压达安全范围,再予(70～208)ug/min静脉维持;B组(25例)采用硝苯地平10mg口服,q8h,两组同时使用硫酸镁预防子痫发生。在此期间监控血压,心电变化。结果:A组用药2h后显效23例,有效6例,显效率76.7%,总有效率96.7%。36h平均血压为(106±13)mmHg(1mmHg=0.133kPa)。B组用药2h后显效8例,有效10例,显效率32%,总有效率72%。36h平均血压为(118.9±10.2)mmHg,出现心动过速8例。结论:拉贝洛尔治疗妊娠高血压急症疗效确切,降压平稳,未见有严重不良反应。
Objective: To observe the efficacy of intravenous labetalol in the treatment of crisis of pregnancy induced hypertension. Methods: Fifty-five hypertensive crisis patients were divided into two groups: group A (30 cases) received labetalol injection (0.5-1 mg / min) , And then (70 ~ 208) ug / min intravenous maintenance; B group (n = 25) nifedipine 10mg orally, q8h, both groups use magnesium sulfate to prevent eclampsia. During this period to monitor blood pressure, ECG changes. Results: In group A, 23 cases were markedly effective after 2 hours and 6 cases were effective. The effective rate was 76.7% and the total effective rate was 96.7%. 36h mean blood pressure was (106 ± 13) mmHg (1mmHg = 0.133kPa). B group 2h after markedly effective in 8 cases, effective in 10 cases, markedly effective rate of 32%, the total effective rate of 72%. 36h mean blood pressure (118.9 ± 10.2) mmHg, tachycardia occurred in 8 cases. Conclusion: Labetalol is effective in treating acute pregnancy induced hypertension and has stable blood pressure and no serious adverse reactions.