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肿瘤坏死因子(TNF)是主要由被激活的单核巨噬细胞释放的一种多功能细胞因子,除了对肿瘤细胞、移植细胞和自身某些组织细胞的炎症坏死作用外,对外周多种组织细胞的能量代谢也有明显的影响。很多资料显示TNF参与糖、脂、蛋白质的代谢活动,尤其在临床创伤感染病人中同时有TNF水平的持续升高和高代谢状况
Tumor necrosis factor (TNF) is a multifunctional cytokine released mainly by activated mononuclear macrophages. In addition to the inflammatory and necrotic effects on tumor cells, transplanted cells and some of its own tissue cells, various tissues The energy metabolism of cells also has a significant effect. A lot of data show that TNF is involved in the metabolic activity of sugar, lipid and protein, especially in the patients with clinical trauma infection, with the continuous increase of TNF level and the high metabolic status