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目的:评价吗叮啉混悬液治疗早产儿喂养困难的疗效。方法:2003年9月～2006年10月住院期间出现喂养困难的早产儿62例。实验组:吗叮啉混悬液0.3mg/kg,Q6h,喂奶前10～30min鼻饲;对照组:红霉素3～5mg/(kg·d),加入10%葡萄糖液20ml缓慢静脉滴注,疗程3～7天。观察奶量开始增加的时间、呕吐溢乳等症状消失的时间。结果:实验组治疗后,进奶量开始增加时间及症状消失时间明显早于对照组(P<0.001)。结论:胃动力药-吗叮啉混悬液治疗早产儿喂养困难安全、价格便宜、有效。
OBJECTIVE: To evaluate the efficacy of morphine suspension in the treatment of premature infant feeding difficulties. Methods: From September 2003 to October 2006, 62 cases of premature infants with difficulty in feeding appeared during hospitalization. The experimental group: Morindrom suspension 0.3mg / kg, Q6h, nasal feeding 10-30min before feeding; control group: erythromycin 3 ~ 5mg / (kg · d), adding 10% glucose solution 20ml slow intravenous drip, Course of 3 to 7 days. Observed the amount of milk began to increase, vomiting galactorrhea and other symptoms disappear time. Results: After the experimental group was treated, the amount of milk intake began to increase and disappeared significantly earlier than the control group (P <0.001). Conclusions: The gastric motility drug-domperidone suspension is safe, cheap and effective for the treatment of premature infants.