A cellular scale numerical study of the effect of mechanical properties of erythrocytes on the near-

• 作 者: Jing Xu Xiao-Long Wang Yun-Qiao Liu Xiao-Bo Gong
• 机 构: MOE Key Laboratory of Hydrodynamics,Department of Engineering Mechanics,Shanghai Jiao Tong Universit
• 出 处: Acta Mechanica Sinica
• 发表日期: 2014年02期
• 关键词: fluctuation negligible immersed approaching capsules stiffness viscous filled nu

The effect of mechanical properties of erythrocytes on the near-wall motion of platelets was numerically studied with the immersed boundary method. Cells were modeled as viscous-fluid-filled capsules surrounded by hyper-elastic membranes with negligible thickness. The numerical results show that with the increase of hematocrit, the near-wall approaching of platelets is enhanced, with which platelets exhibit larger deformation and orientation angle of its near-wall tank-treading motion, and the lateral force pushing platelets to the wall is increased with larger fluctuation amplitude. Meanwhile the near-wall approaching is reduced by increasing the stiffness of erythrocytes.

The effect of mechanical properties of erythrocytes on the near-wall motion of platelets was numerically studied with the immersed boundary method. Cells were modeled as viscous-fluid-filled capsules surrounded by hyper-elastic membranes with negligible thickness. The numerical results show that with the increase of hematocrit, the near-wall approaching of platelets is enhanced, with which platelets exhibit larger deformation and orientation angle of its near-wall tank-treading motion, and the lateral force pushing platelets to the wall is increased with larger fluctuation amplitude. Meanwhile the near-wall approaching is reduced by increasing the stiffness of erythrocytes.