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一名例产前妇女,血型为OR1R1型,16周时血清中出现抗-E抗体。前两次怀孕的婴儿直接抗球蛋白试验(DAT)阳性,但不需输血,其配偶表型为R2r。在23周,病人的血清化学发光测试,为119％,表明有活性抗体。26周时对羊水进行分光光度测量分析,在预测新生儿溶血病(HDN)lileychart图的中间区,从羊水细胞提取的胎儿DNA表明胎儿为R1R2型,超声监测表明29周时胎儿发生了贫血,于是进行宫内输血(IUT)。输血前后
An example of prenatal women, blood type OR1R1 type, 16 weeks of serum anti-E antibody. The first two pregnancies were positive for the direct antiglobulin test (DAT) but did not require blood transfusions, with a spouse phenotype of R2r. At 23 weeks, the patient’s serum chemiluminescence test was 119%, indicating that there was an active antibody. At week 26, amniotic fluid was measured spectrophotometrically and, in the middle of the lileychart map for prediction of neonatal hemolytic disease (HDN), fetal DNA extracted from amniotic fluid cells showed that the fetus was R1R2 type. Ultrasound monitoring indicated that the fetus developed anemia at week 29, Then intrauterine transfusion (IUT). Before and after transfusion