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本文报道20例遗传性球形细胞增多症(HS),15例溶血性贫血(溶贫)及45例正常初生～12岁小儿微量外周血酸化甘油溶解试验测定值(AGLT_(50)),20例HS AGLT_(50)均<100秒。14例溶贫及45例正常小儿AGLT_(50)均>290秒。与红细胞渗透脆性试验等其它有关实验室指标比较,AGLT对HS诊断具有一定特异性及敏感性。适合儿科临床应用,并适用于HS家系调查。
This article reports 20 cases of hereditary hypersplenism (HS), 15 cases of hemolytic anemia (Poverty-poor) and 45 cases of normal newborn to 12-year-old pediatric trace amount of glycerol dissolved glycerol dissolution test (AGLT_ (50) HS AGLT_ (50) are <100 seconds. 14 cases of poor and 45 cases of normal children AGLT_ (50) were> 290 seconds. Compared with other relevant laboratory indexes such as the erythrocyte infiltration fragility test, AGLT has certain specificity and sensitivity to HS diagnosis. Suitable for pediatric clinical applications and for HS pedigree investigation.