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整合素(integrin)是由不同α和β亚基组成的异二聚体跨膜糖蛋白,属于细胞表面黏附分子,主要由胞外区(extracellu-lar domain)、跨膜区(transmembrane domain)和胞内区(intra-cellular domain)3部分组成。整合素通过双向信号传导通路介导细胞与细胞间及细胞与细胞外基质(extrace
Integrin is a heterodimeric transmembrane glycoprotein composed of different α and β subunits. It belongs to the cell surface adhesion molecule and is mainly composed of extracellular-lar domain, transmembrane domain and Intracellular domain (intra-cellular domain) 3 parts. Integrins mediate cell-cell and intercellular-cell and extracellular matrix