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本实验通过在大鼠输卵管腔内注入15%苯酚糊剂建立输卵管炎性阻塞模型,观察毛冬青甲素对该模型组织学和血液流变学的影响,旨在探讨毛冬青甲素对输卵管炎性阻塞的防治作用。结果表明:毛冬青甲素能抑制输卵管炎所致的结缔组织增生,对抗粘膜上皮的变性坏死,抑制炎症的浸润。用药组与对照组比较,差异有显著性意义(P<0.05～0.01)。同时,造模大鼠经用药后其血液比粘度、红细胞电泳率、红细胞聚集指数等指标显著改善。为毛冬青甲素治疗输卵管炎性阻塞提供了初步依据。
In this experiment, a 15% phenol paste was injected into the oviduct of rats to establish an occlusion model of oviductal obstruction. The effect of scopolamine on the histology and hemorheology of the model was observed. The aim was to investigate the effect of oxydoprine on salpingitis Prevention of sexual obstruction. The results showed that Maodongqingsu can inhibit the proliferation of connective tissue caused by salpingitis, counteract the degeneration and necrosis of mucosal epithelium, and inhibit the infiltration of inflammation. The difference between the drug group and the control group was significant (P<0.05-0.01). At the same time, the blood viscosity, red blood cell electrophoresis, and red blood cell aggregation index of the model rats were significantly improved after administration. It provides a preliminary basis for the treatment of salpingitis occlusion by Maodongqingsu.