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霉菌毒素在肿瘤病因学中的作用日益受到人们的重视。互隔交链孢霉毒素是继黄曲霉毒素被证明具有致肝癌作用之后又一个引起肿瘤病因研究者关注的霉菌毒素。食管癌高发区林县粮食中互隔交链孢霉的污染率及其毒素的检出率均高于低发区商丘相应粮食中的污染率及其毒素检出率。该菌培养物的粗提物又具有诱变作用和细胞转化作用,并初步诱
The role of mycotoxins in the etiology of tumors has received increasing attention. Alternaria alternata is a mycotoxin that has attracted the attention of researchers after the aflatoxin was proved to have liver cancer. The contamination rate of Alternaria alternata and the detection rate of toxins in Linxian County, a high-incidence area of esophageal cancer, were higher than those in Shangqiu, a low-incidence area, and the toxin detection rate. The crude extract of the bacterial culture also has mutagenesis and cell transformation effects, and is initially induced