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视网膜母细胞瘤是儿童中最常见的眼内恶性肿瘤。作者发现本病患者房水中烯醇化酶亚单位浓度增高。这些酶可作为本病的诊断和监测指标。作者切取5例视网膜母细胞瘤组织,经离心从瘤组织匀浆中收集上清液。房水和脑脊液标本由19例视网膜母细胞瘤(其中5例怀疑该瘤侵及脑膜)及1例青光眼患者抽取。均贮存于-80℃,直至使用。对各标本的烯醇化酶亚单位浓度均作免疫测定。结果:切除的5例视网膜母细胞瘤组织中,烯醇化酶γ-亚单位浓度高达1,660～8,
Retinoblastoma is the most common intraocular malignancy in children. The authors found that patients with aqueous hyaluronidase subunit concentrations increased. These enzymes can be used as the diagnosis and monitoring indicators of the disease. The authors cut five cases of retinoblastoma tissue and centrifuged to collect the supernatant from the tumor tissue homogenate. Aqueous humor and cerebrospinal fluid were collected from 19 patients with retinoblastoma (5 of whom suspected this tumor invasion and meninges) and 1 patient with glaucoma. Store at -80 ° C until use. The enolase subunit concentrations of each specimen were measured by immunoassay. Results: The excised 5 cases of retinoblastoma tissue, enolase γ-subunit concentration as high as 1,660 to 8,