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有机磷农药是常用农药种类,因误服过量可能导致中毒反应,且可能威胁患者生命。导泻是救治有机磷农药口服中毒中的重要环节,是利用导泻剂促进排便,并促进积蓄、游离在胃肠道内的毒物排出,可有效提高患者抢救成功率,降低病死率。目前临床常见的导泻剂包括甘露醇、大黄等,效果各异,且可联合使用,但需注意适宜的使用剂量及方法,保证患者的安全。
Organophosphorus pesticides are common types of pesticides. Overexposure to oral ingestion may cause toxic reactions and may threaten the patient’s life. Catharsis is an important part in the treatment of oral organophosphate pesticides poisoning. It is the use of cathartic agents to promote defecation, and promote savings, free of toxic substances in the gastrointestinal tract discharge, which can effectively improve the success rate of rescue and reduce mortality. Currently common clinical purgatives include mannitol, rhubarb, with different effects, and can be combined, but should pay attention to the appropriate dosage and methods to ensure the safety of patients.