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目的:探讨丙泊酚联合地佐辛在无痛人流术中的疗效及安全性。方法:选取我院2013年11月-2016年11月行无痛人流终止妊娠的早孕妇女80例,随机分为观察组(丙泊酚+地佐辛)和对照组(丙泊酚)各40例。对比两组唤醒时间、诱导时间、定向力恢复时间、丙泊酚总量、人流时间、体动次数、呼吸抑制发生率、恶心呕吐发生率和VAS评分。结果:观察组唤醒时间、定向力恢复时间和丙泊酚总量均显著少于对照组(P<0.05)。两组诱导时间比较,差异无统计学意义(P>0.05)。观察组呼吸抑制发生率和VAS评分均显著少于对照组(P<0.05)。两组人流时间、体动次数和恶心呕吐发生率比较,差异无统计学意义(P>0.05)。结论:无痛人流术中应用丙泊酚联合地佐辛麻醉效果良好,安全性较好,值得临床推广。
Objective: To investigate the efficacy and safety of propofol combined with dezocine in painless abortion. Methods: Eighty pregnant women with painless termination of pregnancy from November 2013 to November 2016 in our hospital were randomly divided into observation group (propofol + dezocine) and control group (propofol) example. The wake time, induction time, recovery time, total propofol, flow time, body movement, respiratory depression, incidence of nausea and vomiting and VAS score were compared between the two groups. Results: The awake time, the recovery time of directional force and the total amount of propofol in the observation group were significantly less than those in the control group (P <0.05). There was no significant difference in induction time between two groups (P> 0.05). The incidence of respiratory depression and VAS scores in the observation group were significantly less than those in the control group (P <0.05). There was no significant difference between the two groups in the time of flow, the frequency of physical activity and the incidence of nausea and vomiting (P> 0.05). Conclusion: The application of propofol combined with dezocine anesthesia in painless abortion is effective, safe and worthy of clinical promotion.