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目的探讨年轻妇女子宫内膜癌预后相关因素。方法回顾性分析2008年3月至2011年3月收治的年龄<40岁的年轻妇女子宫内膜癌患者185例,根据随访3年后的最终结果分为死亡组与生存组,对临床资料、预后相关因素进行分析。结果经随访3年发现,年轻妇女子宫内膜癌患者3年生存率为87.3%。死亡组与生存组患者比较,在BMI、ER(+)、PR(+)、合并PCOS、病理分期、肌层浸润深度、宫颈浸润情况和淋巴结转移方面差异有统计学意义(P<0.05)。结论 BMI、ER(+)、PR(+)、病理分期、淋巴结转移是影响子宫内膜癌预后的独立危险因素,BMI较大,ER(+)及PR(+)率较低,病理分期较晚,且有淋巴结转移的患者预后可能较差。
Objective To investigate the prognostic factors of endometrial cancer in young women. Methods A retrospective analysis of 185 women with endometrial cancer of young women <40 years of age treated from March 2008 to March 2011 was divided into the death group and the survival group according to the final results of 3 years follow-up. The clinical data, Prognosis-related factors were analyzed. Results After 3 years of follow-up, the 3-year survival rate of young women with endometrial cancer was 87.3%. There were significant differences between BMI, ER (+), PR (+), PCOS, pathological stage, depth of myometrial invasion, cervical infiltration and lymph node metastasis in the death group and the survival group (P <0.05). Conclusions BMI, ER (+), PR (+), pathological stage and lymph node metastasis are independent risk factors for prognosis of endometrial carcinoma. BMI is higher, and ER (+) and PR (+ Patients with nocturnal and lymph node metastases may have poor prognosis.