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目的 观察升气养元糖浆的补血作用和对脾虚所致各种症状的保护作用。方法 采用失血性贫血模型以及口服大黄或甘蓝 +猪油或皮下注射利血平造成的脾虚模型 ,用药后测定相应的指标。结果 升气养元糖浆 9.0、 3 .0 g/ kg(折合成生药量 ,下同 ) ,使失血性贫血小鼠的血红蛋白 ( Hb)分别提高 8.0、 1 2 .5g/ L,红细胞数也有增加的趋势 ;提高大黄引起的脾虚小鼠的脾脏重量 ,并使血清溶血素 ( HC50 )水平分别提高 3 7.9%和 4 3 .0 % ,血清凝集素 ( K)水平分别提高 1 0 .2 %和 1 7.5% ;升气养元糖浆 4 .5、 1 .5g/ kg使利血平引起的脾虚小鼠的木糖吸收功能明显提高 ;使甘蓝和猪油引起的脾虚小鼠状态明显改善 ,并且存活时间延长。结论 提示升气养元糖浆具有补血 ,健脾和增强免疫功能的作用。
Objective To observe the blood-enhancing effect of Shengqi Yangyuan Syrup and its protective effect on various symptoms caused by spleen deficiency. Methods The model of spleen deficiency caused by hemorrhagic anemia model and oral rhubarb or cabbage + lard or subcutaneous injection of reserpine was used to measure the corresponding indicators after administration. Results 9.0 and 3.0 g/kg of Shengqi Yangyuan Syrup (combined crude drug dosage, the same below) increased hemoglobin (Hb) in hemorrhagic anaemia mice by 8.0 and 12.5 g/L, respectively, and the number of red blood cells also increased. The trend was to increase spleen weight in mice with spleen deficiency caused by rhubarb, and to increase levels of serum hemolysin (HC50) by 3 7.9% and 43.0 % respectively, and serum lectin (K) levels by 10.2% and 1 7.5%; LHY syrup 4.5%, 1.5g/kg significantly increased xylose uptake in mice with spleen deficiency caused by reserpine; significantly improved the status of spleen deficiency mice caused by cabbage and lard; Survival time is extended. Conclusion It is suggested that Shengqiyangyuan Syrup has the functions of blood supplement, spleen and enhancement of immune function.