论文部分内容阅读
啮齿类动物全胚胎培养(Whole EmbryoCulture WEC)最初是由Nicholas和Rudnik(1934,1938)进行实验,获得成功。70年代由New等对此项体外培养技术进行了较大改进。由于该方法具有快速、经济、能够准确控制胚外暴露,并能排除母体对致畸原的影响等优点,近年来在毒理学领域中已用于化学物质致畸性的检验、快速筛选
The Whole Embryo Culture WEC was originally tested by Nicholas and Rudnik (1934, 1938) for success. In the 1970s, New et al made great improvements to this in vitro culture technique. The method has been used in the field of toxicology for the test of teratogenicity of chemicals in recent years due to its advantages of fastness, economy, accurate control of extra-embryonic exposure and elimination of maternal effects on teratogens. Rapid screening