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肺癌是当今世界各国常见恶性肿瘤,严重影响人类健康。早期诊断是改善肺癌预后的关键。某些遗传学改变和表观遗传学改变等分子异常均可发生在肺癌癌前病变及早期癌中,为肺癌早期诊断提供了理论基础,生物芯片等分子生物学技术的迅猛发展进一步拓展了分子标志物应用前景。
Lung cancer is a common malignancy in all countries of the world and seriously affects human health. Early diagnosis is the key to improve the prognosis of lung cancer. Some genetic changes and epigenetic changes and other molecular abnormalities can occur in precancerous lesions and early lung cancer, providing a theoretical basis for the early diagnosis of lung cancer. The rapid development of molecular biology techniques such as biochips further expands the molecular Marker application prospects.