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作者将用蜜蜂产品蜂胶制成的蜂胶牙泰(酊剂)用于治疗冠周炎,同时与1%碘甘油对比观察,以评价蜂胶牙泰的临床疗效及体内抑菌作用。选冠周炎患者60例,试验组45例(其中30例同时兼作体内抑菌试验),对照组15例。体内抑菌试验结果表明30例经蜂胶牙泰治疗后冠周袋内5种主要致病菌菌落数、厌氧菌总数、需氧菌总数、总菌数明显下降(P<0.01),而15例经1%碘甘油治疗后盲袋内细菌数下降不明显(P>0.05)。临床实验研究结果,蜂胶牙泰组有效率为48.9%,1%碘甘油组有效率为20.0%(P<0.05)。蜂胶牙泰治疗冠周炎临床疗效优于传统药物1%碘甘油,且对口腔粘膜无刺激无毒副作用,是一种有前途的冠周炎局部用药。
The authors will use bee propolis made of propolis toothpaste (tincture) for the treatment of pericoronitis, while compared with 1% iodine glycerol to evaluate the clinical efficacy of propolis toothpaste and in vivo antibacterial effect. Pericoronitis patients selected 60 cases, 45 cases in the experimental group (of which 30 also served as antibacterial test in vivo), the control group of 15 patients. The results of antibacterial test in vivo showed that the number of colonies, the total number of anaerobic bacteria, the total number of aerobic bacteria and the total number of bacteria in the perianal pocket of 30 cases decreased significantly after propolis toothpaste treatment (P <0.01) In 15 cases, the number of bacteria in blind bag after treatment with 1% iodine glycerol was not significantly decreased (P> 0.05). The results of clinical trials, the effective rate was 48.9% propolis tooth group, 1% iodine glycerol group was 20.0% (P <0.05). Propolis Tooth Thailand pericoronitis treatment of clinical efficacy is better than the traditional drugs 1% iodine glycerol, and non-toxic to the oral mucosa non-toxic side effects, is a promising pericoronitis topical drug.