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支气管哮喘是一种危害患儿身心健康且与变态反应有关的疾病.为了探讨哮喘患儿变应原与IgG亚类的关系,对100例哮喘患儿作了变应原皮试,同时进行了血清IgG亚类的检测,报告如下:1 材料和方法1.1 哮喘患儿的筛查 按《全国小儿呼吸道疾病学术会议》提出的标准,筛查患儿100例作为观察组.其中男64,女36例;年龄3～7岁42人,8～14岁58人.设对照组30例,为无变态反应个人史及家族史的正常同龄儿.1.2 方法 变应原皮试采用皮内注射法,变应原由北京协和医院变态反应科提供.皮试反应的分级标准按国内文昭明标准(中华儿科杂志,1984;22:213).1.3 血清IgG亚类的检测 采用ELISA法,McAb由重庆医科大学提供.2 结果2.1 变态反应皮试结果 观察组变应原皮试阳性
Bronchial asthma is a kind of disease that endangers children’s physical and mental health and is associated with allergy.In order to investigate the relationship between allergen and IgG subclasses in children with asthma, 100 cases of asthma children were made of allergen skin test, at the same time, serum IgG subclass of the test, the report is as follows: 1 Materials and methods 1.1 screening of children with asthma According to the “National Pediatric Respiratory Disease Symposium,” the proposed screening of 100 cases of children as the observation group, of which male 64, female 36 ; Aged 3 to 7 years old 42 people, 8 to 14 years old 58. The control group of 30 cases, with no personal history of allergy and family history of normal peers.1.2 Methods Allergen skin test using intradermal injection, allergy Originally provided by the Beijing Union Medical College Hospital Department of Allergy. Skin test response grading standards according to the domestic text Zhaoming standard (China Pediatrics, 1984; 22: 213) .1.3 serum IgG subclasses using ELISA method, McAb provided by Chongqing Medical University. 2 Results 2.1 allergic skin test results observed group allergic skin test positive