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1995年夏季江苏省长江沿线遭受洪水侵袭，50余万军民参加抗洪抢险。而长江两岸江滩遍布钉螺，其中四分之一为阳性螺滩，钉螺阳性率为0．1％－11．5％。经系统调查，有50320人在抗洪抢险中接触疫水。于接触疫水后第5wk，48688人（96．7％）服用了吡喹酮。无1例罹患急性血吸虫病。其中在南京市龙潭镇江滩曾有2250名人员下水抢险，一月后全部服用吡喹酮，无1例发生急性血吸虫病，而同期在同一地区，盐城市一运输船队路过，被要求协助抗洪抢险，事后未服吡喹酮，一个多月后，60名船员中45人发生急性血吸虫病。结论：在抗洪抢险中大规模应用吡喹酮防治急性血吸虫病是有效而可行的，副作用轻，经济效益高。
In the summer of 1995, floods hit the Yangtze River in Jiangsu Province and more than 500,000 civil and military people took part in flood fighting and rescue. On the banks of the Yangtze River, there are many snails around the snail, of which one quarter are positive snails. The positive rate of snails is 0.1% -11.5%. After systematic investigation, there were 50320 people exposed to floodwaters in flood fighting and rescue. Praziquantel was administered to 48,688 people (96.7%) at 5 weeks after exposure to water. None of the patients had acute schistosomiasis. Among them, 2250 people in the bank of Longtan Town of Nanjing had plunged into the water and took praziquantel after January. None of the patients had acute schistosomiasis. In the same period, a transport fleet in Yancheng passed by and was asked to help fight floods Rescue, did not take praziquantel afterwards, more than a month later, 45 crew of 60 crew members had acute schistosomiasis. Conclusion: It is effective and feasible to use large-scale praziquantel in the prevention and treatment of acute schistosomiasis in flood fighting and rescue. The side effects are light and the economic benefits are high.