Carbenoxolone pretreatment and treatment ofposttraumatic epilepsy

• 作 者: Weiguan Chen Zhiwei Gao Yaohui
• 机 构: DepartmentofRehabilitationMedicine,DepartmentofNeurology
• 出 处: 中国神经再生研究：英文版
• 发表日期: 2013年2期
• 关键词: 酸预处理 癫痫 神经胶质 缝隙连接 细胞增殖 连接蛋白 三价铁离子 放电频率 neural regeneration brain injury posttrau
• 基金项目: supported by the Social Development Program of Nantong, No. S2009035

Gap junction blocking agents can inhibit spontaneous discharge frequency in cells. We established a rat model of posttraumatic epilepsy induced using ferric ions. Rats were intraperitoneally injected with carbenoxolone, 20 mg/kg, prior to and 30 minutes a