论文部分内容阅读
目的:分析轮状病毒感染对婴幼儿心肌的损伤及相关影响。方法:选择我院收治的轮状病毒感染患儿164例,根据是否发生心肌损伤分为观察组60例与对照组104例。对两组患儿的心电图、心肌酶谱和心肌肌钙蛋白I(c Tn-I)进行检测对比。分析年龄、机体代谢紊乱等因素对轮状病毒感染患儿心肌功能的影响,并比较观察组患儿治疗前后心肌酶谱指标的变化。结果:观察组心肌酶谱CK、CK-MB、AST、LDH、LDH1、CTn-I、LDH1/LDH2测定值均显著高于对照组(P<0.05);年龄<1岁、中重度脱水、腹泻、低钾血症以及酸中毒为发生心肌损伤的高危因素;经治疗后心肌损伤的患儿心肌酶谱指标比治疗前均显著降低(P<0.05)。结论:年龄<1岁、脱水、腹泻、低钾血症以及酸中毒严重的轮状病毒感染患儿容易发生心肌损伤,临床上应加强对其心肌酶谱的检测,在治疗腹泻基础上注意对心肌功能的保护,做到早诊早治,以避免患儿心肌功能的进一步损伤。
Objective: To analyze the damage of infants and young children with rotavirus infection and its related effects. Methods: A total of 164 children with rotavirus infection admitted to our hospital were divided into observation group (60 cases) and control group (104 cases) according to whether myocardial damage occurred. Electrocardiogram, myocardial enzymes and cardiac troponin I (cTn-I) were compared between the two groups. Analysis of age, the impact of metabolic disorders and other factors on myocardial function in children with rotavirus infection, and compared changes in myocardial enzymes before and after treatment in children in the observation group. Results: The CK, CK-MB, AST, LDH, LDH1, CTn-I and LDH1 / LDH2 in the observation group were significantly higher than those in the control group (P <0.05) , Hypokalemia and acidosis were risk factors of myocardial injury. Myocardial zymogram of myocardial damage after treatment was significantly lower than before treatment (P <0.05). Conclusion: Children aged <1 year, dehydration, diarrhea, hypokalemia and rotavirus infection with severe acidosis are prone to myocardial injury. Clinically, myocardial enzymes should be checked and diarrhea treated Protection of myocardial function, so early diagnosis and treatment to prevent further damage in children with myocardial function.