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目的:探讨氨氯地平联合卡托普利治疗冠心病合并高血压的临床疗效。方法:将我院2009年6月到2011年9月收治的冠心病合并高血压患者80例随机分为对照组与观察组,每组40例,对照组给予氢氯噻嗪、尼群地平以及硝酸异山梨酯等常规治疗方法,观察组给予氨氯地平联合卡托普利治疗。观察两组的血压控制情况,比较两组患者心绞痛以及心电图改善情况。结果:观察组治疗后的血压明显低于对照组(P<0.05),具有统计学意义;且观察组治疗后的心绞痛以及心电图疗效均明显优于对照组(P<0.05),具有统计学意义。结论:氨氯地平联合卡托普利治疗冠心病合并高血压的临床疗效确切,值得推广应用。
Objective: To investigate the clinical efficacy of amlodipine combined with captopril in the treatment of coronary heart disease complicated with hypertension. Methods: Eighty patients with coronary heart disease complicated with hypertension admitted in our hospital from June 2009 to September 2011 were randomly divided into control group and observation group, 40 cases in each group. The control group was given hydrochlorothiazide, nitrendipine and isosorbide dinitrate Ester and other conventional treatment methods, the observation group was given amlodipine combined with captopril treatment. Blood pressure control was observed in both groups, and angina pectoris and electrocardiogram improvement were compared between the two groups. Results: The blood pressure in the observation group was significantly lower than that in the control group (P <0.05), and was statistically significant. The angina pectoris and ECG after treatment in the observation group were significantly better than those in the control group (P <0.05) . Conclusion: Amlodipine combined with captopril in the treatment of coronary heart disease complicated with hypertension clinical curative effect is worthy of promotion.