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目的:探究子宫动脉栓塞与手术切除治疗对子宫腺肌症患者血清基质金属蛋白酶(MMP)含量及卵巢功能的影响。方法:将我院收治的60例子宫肌腺症患者依入院顺序分为两组,均30例。对照组采用手术切除治疗,观察组采用子宫动脉栓塞治疗,对比两组患者治疗后血清MMP含量及卵巢功能。结果:观察组治疗后血清MMP-2、MMP-3、MMP-9含量均低于对照组,差异显著(P<0.05);治疗后观察组雌激素(E2)、促卵泡激素(FSH)、黄体生成素(LH)水平均明显优于对照组,差异显著(P<0.05)。结论:子宫动脉栓塞可良好保护子宫肌腺症患者卵巢功能,降低术后血清MMP含量。
Objective: To investigate the effect of uterine arterial embolization and surgical resection on serum matrix metalloproteinase (MMP) and ovarian function in patients with adenomyosis. Methods: 60 cases of myasthenia gravis admitted to our hospital were divided into two groups according to the sequence of admission, both of which were 30 cases. The control group was treated by surgical resection. The observation group was treated by uterine artery embolization. The serum MMP level and ovarian function were compared between the two groups after treatment. Results: The levels of serum MMP-2, MMP-3 and MMP-9 in the observation group were significantly lower than those in the control group (P <0.05). After treatment, the levels of estrogen, FSH, Luteinizing hormone (LH) levels were significantly better than the control group, the difference was significant (P <0.05). Conclusion: Uterine artery embolization can protect ovarian function of patients with adenomyosis and decrease serum MMP.