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Fetal complete atrioventricular bl ock(AVB)occurs in 2-5%of Sjgren’s antibodies(SSA /SSB)-positive preg-nancies with substantialmorbidity andmortality.We evalu-ated the incidence of 1°and 2°AVB by m easuring Doppler -derived mechanical PR inte rvals.We compared mechanical PR intervals of fetuses o f SSA /SSB positive mothers referred to a single cardiology center between 1997and 2003with control fetuses and fetuses with 1°or 2°AVB confirmed by magnetocardiography o r postnatal electrocar-diogram.One hundred thirty -nine fe tal echocardiograms performed on 59SSA /SSB -positive pr egnant women at24.3±5.0weeks gestation were compared with 150controls.Mechanical PR intervals o f the study group(120.5±9.8milliseconds)and controls(120.6±8.7milliseconds)were the same but differed significa ntly fromfetuses with 1°and 2°AVB(191.5±29.6msec).The in-cidence of 1°and°2fetal AVB in SSA /S SB -positive pregnancies is low and can be identif ied by abnormal me-chanical PR interval.
Fetal complete atrioventricular block (AVB) occurs in 2-5% of Sjögren’s antibodies (SSA / SSB) -positive preg-nancies with substantial morbidity andmortality. We evaluate-ated the incidence of 1 ° and 2 ° AVB by m easuring Doppler -derived mechanical PR inte rvals. We compared mechanical PR intervals of fetuses of SSA / SSB positive mothers referred to a single cardiology center between 1997 and 2003 with control fetuses and fetuses with 1 ° or 2 ° AVB confirmed by magnetocardiography or postnatal electrocar- diogram. One hundred thirty -nine fe tal echocardiograms performed on 59SSA / SSB-positive and egnant women at 24.3 ± 5.0weeks gestation were compared with 150controls.Mechanical PR intervals of the study group (120.5 ± 9.8milliseconds) and controls (120.6 ± 8.7milliseconds) were the same but differed significantly fromfetuses with 1 ° and 2 ° AVB (191.5 ± 29.6 msec). The in-cidence of 1 ° and ° 2fetal AVB in SSA / S SB -positive pregnancies is low and can be identified by abnormal me-chanical PR interval.