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目的:观察中西医结合治疗小儿过敏性紫癜性肾炎的临床疗效。方法:将64例患儿随机分为两组,均采用口服中药汤剂加减治疗。治疗组在此基础上加用低分子肝素钙,疗程均为4周。对治疗前后疗效、24h尿蛋白、12h尿红细胞计数进行统计学比较。结果:治疗组总有效率93.75,对照组总有效率84.37,两组疗效有显著性差异(P<0.05)。治疗组降低24h尿蛋白及尿红细胞疗效优于对照组。结论:活血益肾汤联合低分子肝素钙可明显改善过敏性紫癜所致的肾损伤,值得临床推广应用。
Objective: To observe the clinical efficacy of traditional Chinese and western medicine in the treatment of children with Henoch-Schonlein purpura nephritis. Methods: 64 cases of children were randomly divided into two groups were treated with oral Chinese medicine decoction. On the basis of the treatment group, low-molecular-weight heparin was used, and the course of treatment was 4 weeks. Before and after treatment efficacy, 24h urine protein, 12h urine red blood cell count for statistical comparison. Results: The total effective rate was 93.75 in the treatment group and 84.37 in the control group, with significant difference (P <0.05). Therapeutic group reduced 24h urinary protein and urinary erythrocytes better than the control group. Conclusion: Huoxue Yishen Decoction combined with low molecular weight heparin can obviously improve renal injury caused by Henoch-Schonlein purpura, which is worthy of clinical application.