论文部分内容阅读
目的 探讨直肠癌术后局部复发诊断及治疗方法。方法 回顾性分析直肠癌根治术后局部复发患者114 例。结果 本组患者中盆腔及会阴复发83 例,吻合口复发20 例,阴道壁复发11 例。81 例(71.1% )手术后2 年内复发,79 例患者有骶神经丛刺激症状。21 例再次手术切除,34 例局部放疗,59 例化疗或其他治疗。再次手术切除与非手术切除治疗3 年生存率分别为57.1% 及4.3% ,5 年生存率 28.6% 及1.1% ,差异有显著性( P< 0.001)。结论 直肠癌根治术后2~3 年内要严密随访,有利于早期发现复发。对局部复发再次手术切除是首选的治疗方法。
Objective To investigate the diagnosis and treatment of local recurrence after rectal cancer. Methods Retrospective analysis of 114 patients with local recurrence after radical resection of rectal cancer. Results In this group of patients, there were 83 cases of pelvic and perineal recurrence, 20 cases of anastomotic recurrence, and 11 cases of vaginal recurrence. Eighty-one patients (71.1%) had recurrence within 2 years after surgery, and 79 patients had spastic plexus irritation. Twenty-one patients underwent reoperation, 34 received local radiotherapy, and 59 received chemotherapy or other treatments. The three-year survival rates for re-surgical and non-surgical resections were 57.1% and 4.3%, respectively, and 5-year survival rates were 28.6% and 1.1%, respectively, with a significant difference (P < 0.001). Conclusion The follow-up of rectal cancer must be followed up within 2 to 3 years after radical resection, which is helpful for the early detection of recurrence. Surgical resection of local recurrence is the preferred treatment.