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目的了解福安市妊娠梅毒发病率,探讨妊娠梅毒筛查、治疗与不良妊娠结局,评价开展预防梅毒母婴传播工作的意义。方法按国家《预防艾滋病、梅毒和乙肝母婴传播工作实施方案》开展预防梅毒母婴传播工作,收集分析2011年12月-2014年3月福安全市分娩产妇的梅毒筛查状况。结果 2011年12月-2014年3月该市有分娩产妇26 818名,其中进行孕期梅毒筛查的孕产妇24 654名,梅毒筛查率91.93%。检出梅毒感染孕产妇409例(334例已结束妊娠、75例尚未分娩),均为隐性梅毒,隐性梅毒占100%,妊娠梅毒发病率16.59‰(409/24 654)。334例已结束妊娠的梅毒感染孕产妇正常妊娠结局316例(占94.61%),不良妊娠结局18例(占5.39%)。规范治疗183例,其正常妊娠结局100%,不良妊娠结局0%;未规范治疗151例,其正常妊娠结局88.08%,不良妊娠结局11.92%。结论开展孕期梅毒筛查,及早发现、及时规范治疗,对预防梅毒母婴传播,改善不良妊娠结局具有重大意义。
Objective To understand the incidence of syphilis in Fuan City, to explore the screening of pregnant syphilis, treatment and adverse pregnancy outcomes, evaluate the significance of prevention of mother-to-child transmission of syphilis. Methods The prevention of mother-to-child transmission of syphilis was carried out in accordance with the “Implementation Plan of HIV / AIDS Prevention, Syphilis and Hepatitis B Mother-to-Child Transmission in China” and the syphilis screening status of pregnant women in childbirth in Fu’an city from December 2011 to March 2014 was collected and analyzed. Results From December 2011 to March 2014, there were 26,818 mothers giving birth in this municipality, of which 24,645 were maternal pregnant women with syphilis screening and 91.93% were using syphilis screening rate. 409 cases of pregnant women with syphilis infection were detected (334 cases have completed pregnancy and 75 cases have not yet delivered), all of them are latent syphilis, with latent syphilis accounting for 100%. The incidence of syphilis in pregnancy is 16.59% (409/24 654). 334 cases of syphilis infection in pregnant women have completed normal pregnancy outcome of 316 cases (94.61%), adverse pregnancy outcomes in 18 cases (5.39%). 183 cases of normative treatment, the normal pregnancy outcome of 100%, adverse pregnancy outcomes 0%; non-standard treatment of 151 cases, the normal pregnancy outcome of 88.08%, adverse pregnancy outcomes of 11.92%. Conclusion To carry out pregnancy screening syphilis, early detection, timely and standardized treatment of syphilis to prevent mother-to-child transmission and improve adverse pregnancy outcomes of great significance.